Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Crystallin alpha A (Heat shock protein)

Seq-ID:

P02470 [Bos taurus]

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Interaction Network(s):

-

External Source(s):

MINT Interaction(s):

-

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
unfolded protein binding, structural constituent of eye lens	cytoplasm	response to heat

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	122	REFHRRYRLPSNVDQSALSCS	-	1956339	LTP	0.79		-	HSP20	0.29	-	medium

Crystallin alpha A (Heat shock protein)

Seq-ID:

P02489 [Homo sapiens]

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Interaction Network(s):

STRING

NetworKIN

External Source(s):

Phosida

MINT Interaction(s):

[show]

MINT-14199   CRBB2_HUMAN
MINT-14641   CRGC_HUMAN
MINT-16434   HSPB1_HUMAN
MINT-17437   CRYAB_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
unfolded protein binding, structural constituent of eye lens	cytoplasm	anti-apoptosis, response to heat, visual perception, protein homooligomerization, negative regulation of intracellular transport

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	13	VTIQHPWFKRTLGPFYPSRLF	-	12060738	LTP	0.10		-	Crystallin	0.06	-	medium
S	45	DLLPFLSSTISPYYRQSLFRT	-	12060738	LTP	0.91		-	Crystallin	0.04	-	medium
S	122	REFHRRYRLPSNVDQSALSCS	-	12060738	LTP	0.82		-	HSP20	0.27	-	medium
T	140	SCSLSADGMLTFCGPKIQTGL	-	12060738	LTP	0.97		-	HSP20	0.26	-	medium

Crystallin alpha A (Heat shock protein)

Seq-ID:

P24622 [Mus musculus]

Download:

Interaction Network(s):

-

External Source(s):

Phosida

MINT Interaction(s):

-

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
structural constituent of eye lens	cytoplasm	positive regulation of protein amino acid phosphorylation, embryonic camera-type eye morphogenesis, response to UV-A, tubulin complex assembly, apoptosis involved in morphogenesis, positive regulation of cell growth, response to hypoxia, response to hydrogen peroxide, lens fiber cell morphogenesis, negative regulation of caspase activity, response to heat, actin filament organization, negative regulation of gene expression, M phase specific microtubule process, mitochondrion organization

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	145	REFHRRYRLPSNVDQSALSCS	-	12856102	LTP	0.23		-	HSP20	0.35	-	high
S	171	MLTFSGPKVQSGLDAGHSERA	-	12856102	LTP	0.19		-	HSP20	0.55	-	high